Synthesis , structural characterization and biological studies of copper complexes with 2 - aminobenzothiazole derivatives

Novel copper complexes of 2-aminobenzothiazole derivatives were synthesized by the condensation of knoevengal condensate acetoacetanilide (obtained from substituted benzaldehydes and acetoacetanilide) and 2-aminobenzothiazole. They were thoroughly characterized by elemental analysis, IR, H-NMR, UV-Vis., molar conductance, magnetic moment and electrochemical studies. The UV-Vis., spectral study suggested that distorted square planar geometry for all the complexes was assigned. Molar conductance data and magnetic susceptibility measurements provide evidence for monomeric and neutral nature of the complexes. The electrochemical behavior of the ligands and complexes in DMSO at 298 K was studied. The present ligand systems stabilize the unusual oxidation states of copper ion during electrolysis. The surface morphology of the ligands and their complexes was studied using SEM. Antibacterial screening of the ligands and their complexes reveal that all the complexes show higher activities than the free ligands. Antioxidant and SOD studies also performed.